Resources

This portal was created for members of the PFSCM community to share information on supply chain efforts worldwide.
We encourage you to download documents, suggest resources and develop this space as a helpful virtual location to collaborate.

News

PFSCM Supply Lines Blog

Resources

This portal was created for members of the PFSCM community to share information on supply chain efforts worldwide.
We encourage you to download documents, suggest resources and develop this space as a helpful virtual location to collaborate.

News

VMMC guide cover

We have known for years that if babies born with HIV do not receive treatment, more than 50 percent will die before their second birthday, but we also know that when treated, they can grow into healthy adults. Until very recently, a big challenge has been reaching mothers and their new babies soon enough, testing baby, and getting the results back to mom. Reliable diagnosis could only be completed in larger laboratories, meaning blood samples had to be transported to the lab, kept fresh for testing, and then the results returned — by which time, mother and baby were probably back in their village and might never get the result.

PFSCM has always been firmly committed to improving the care, detection, and treatment of the youngest patients. Drawing on our expertise in managing global supply chains and optimizing laboratory networks, our contribution will be to ensure that the supply chain doesn’t let these patients down; that smart network design places these new instruments where they will make the most difference; and that results get back to mom and her health caregivers at the earliest opportunity.

Read more at our PFSCM Supply Lines blog.

VMMC guide cover

The Under the auspices and funding of SCMS, has developed a new comprehensive toolkit that provides guidance on health care waste management (HCWM) and environmental hygiene best practices for VMMC services. The toolkit is available for download on USAID’s AIDSFree website.

The toolkit contains two components — program guidance and site guidance — each of which is based on VMMC program experience, WHO guidance, and USAID environmental protection/compliance regulations.

Program guidance

The resources in the toolkit’s program guidance component provide VMMC implementing partners with guiding principles for the design, implementation, and monitoring of VMMC environmental health programs. Resources include:

  • A program management guide on safer HCWM practices in VMMC programs
  • Assessment tools
  • Incident management tools
  • Audit tools
  • Disposal guidance for unusable medical products
  • Disposal guidance for unusable pharmaceutical products 

Site guidance

In the site guidance component of the toolkit, the resources provide health service providers with specific guidance and tools to teach and reinforce environmental health management. Resources include:

  • A site management guide on environmental health management in VMMC programs
  • Training materials, including a staff pocket guide with a key ring
  • Posters
  • Assessment tools
  • Incident management tools
  • Monitoring tools
  • Disposal guidance for unusable medical products
PAPWG

Through the support of PEPFAR, the President’s Malaria Initiative (PMI), and USAID, PFSCM and the USAID | DELIVER PROJECT contributed to strengthening Zambia’s public health supply chain for HIV/AIDS medicines, malaria medicines, essential medicines, and family planning products. The projects worked to build the capacity of the Government of Zambia (GRZ) to ensure the availability and security of vital health commodities at service level sites by:

  • Strengthening logistics systems to avail critical data for informed supply chain decision making;
  • Increasing ownership to conduct coordinated, transparent quantification, procurement planning, and supply monitoring;
  • Providing cost effective,reliable procurement services;
  • Reinforcing infrastructure for warehousing, distribution, and testing; and
  • Improving strategic management and planning for increased commodity security.

Check out this video to learn more about the supply chain challenges faced when the two projects began and the achievements brought about through collaboration with the Ministry of Health, Medical Stores Limited (MSL), and other partners. The video also looks ahead at the future of the supply chain in Zambia, with recipient, implementer, and donor testimony.

IATT paediatric updated ARV formulary and limited-use list: 2016 update

The 2016 update to the IATT Paediatric ARV Formulary and Limited-Use List has now been officially endorsed by both WHO and UNICEF and is available online.

The first IATT optimal paediatric ARV formulary was created in 2011 by the Child Survival Working Group and the Supply Chain Management Working Group of the Interagency Task Team (IATT) on the Prevention and Treatment of HIV Infection in Pregnant Women, Mothers, and Children. Since then, the group has convened in conjunction with the ARV Procurement Working Group (APWG) every six months, and following any updates from the WHO Consolidated ARV Guidelines, to update the existing optimal paediatric ARV formulary. This edition reflects the 2016 WHO Consolidated Guidelines and takes account of changes in the markets.

The list continues to serve as guidance for national programs, procurement agencies, funders, and manufacturers to select products that closely align to the criteria describing optimal paediatric dosage forms.

PAPWG

A new paper from the Global Fund and UNITAID describes how the challenging market for paediatric anti-retroviral medicines has been transformed.

The Paediatric ARV Procurement Working Group (PAPWG) was established in 2011 to address procurement and access challenges in the small and highly fragile paediatric ARV market. The Working Group was established as a global collaboration and coordination, including major financiers and procurers of ARVs, as well as technical bodies, through procurement promoting optimal products and regimens. Bringing these partners together enabled greater visibility into this fragile market than any one partner could achieve alone. The PAPWG’s leadership and successful management of the paediatric ARV market has ensured an uninterrupted supply and treatment for children living with HIV. PFSCM and SCMS were founding members of the PAPWG.

The paper and lessons learned can be found here.

The approach taken by the Working Group is now being applied to other commodities and health interventions with similar market conditions. In early 2016, the PAPWG expanded its mandate to include specialist adult ARVs facing similar market challenges, and to support the scale-up of new optimal regimens and formulations.

warehouse workers

The UNAIDS “90-90-90” strategy calls for 90% of HIV-infected individuals to be diagnosed by 2020, 90% of whom will be on ARTs and 90% of whom will achieve sustained virologic suppression. Reaching these targets by 2020 will reduce the HIV epidemic to a low-level endemic disease by 2030. From a supply chain perspective, each of the “90’s” has possible complications and roadblocks towards realizing the promise envisioned by 90-90-90.

Read a “real world analysis” of these proposed strategies and policies in our article “The 90 90 90 strategy to end the HIV Pandemic by 2030: Can the supply chain handle it?” just published in the Journal of the International AIDS Society.

mother and child

The new, scored, fixed-dose combination (FDC) tablet containing 120 mg of Abacavir (ABC) and 60 mg of Lamivudine (3TC) is available for procurement through Mylan.

This formulation can significantly decrease pill burden in children (by at least 50% compared to existing formulations of ABC), particularly when used as a once-daily regimen. The reduced pill burden may improve patient adherence and simplify the supply chain at no additional cost to national HIV programs. Furthermore, this formulation may prevent sub-optimal dosing that occurs when adult formulation tablets are cut for use by children.

For further background and a dosing chart for quantification of ABC/3TC (120/60 mg) requirements by weight band, please see the information briefs available in English, French, and Spanish.

ABC/3TC (120/60 mg) Tablet Informational Brief

Note d’information sur les comprimés d’ABC/3TC (120/60 mg)

Nota informativa sobre la pastilla ABC/3TC (120/60 mg)

Storage facilities are critical in ensuring that people can receive the life-saving medicines they need for survival. Without proper storage, drugs can lose potency, become damaged or even be stolen. Earlier this year, SCMS began the deployment of 115 storage-in-a-box (SiB) units in Malawi, funded by USAID and the Department for International Development (DFID).

To learn more, check out the MBC News video, taken during the launch of the first SiB at the Chitedze Health Centre in Lilongwe. It features interviews with Ministry of Health Principal Secretary Mc Phail Magwira, USAID Mission Director Doug Arbuckle, and DFID head in Malawi, Philip Smith, on this critical effort.

mowafy picture

USAID published a great story about SCMS in its USAID Impact Blog titled, “Delivering Life-Saving HIV/AIDS Drugs Around the World” by Sherif Mowafy. It highlights the importance of supply chains in public health and cites some of SCMS’s many successes and impacts. This story further promotes our SCMS 10 Year Review, “Ten Years of Supporting PEPFAR through Stronger Public Health Supply Chains.”

pepfar hands holding ribbon

SCMS is proud to release its report, “10 Years of Supporting PEPFAR through Stronger Public Health Supply Chains: A Report on SCMS Contributions to PEPFAR Results.” As SCMS marks a decade of operating the largest public health supply chain in the world on behalf of the US government, the project looks back at how it helped to move the global community closer to reaching our collective goal: achieving an AIDS-free generation.

At the International AIDS Conference in July in Durban, South Africa, PFSCM conducted a satellite panel discussion with the theme of “Meeting the Supply Chain Challenge of 90-90-90.” The 90-90-90 targets have a number of ramifications on the various elements of the supply chain.

Five panelists representing UNAIDS, which established the 90-90-90 goals; WHO, which develops related policy and guidance; Mylan, an ARV manufacturer; Alere, a diagnostics manufacturer; and Imperial Health Sciences, a health logistics firm and PFSCM partner, engaged in thought-provoking discussion to unpack the challenges facing each 90.

PFSCM’s David Jamieson introduced the panel discussion and framed the discussion around innovations needed to achieve the 90-90-90 goals. With PFSCM’s Gordon Comstock moderating the panel, Peter Ghys of UNAIDS and Daniel Low-Beer of WHO spoke about the modeling that led to 90-90-90 and the innovations needed to treat all. Arvind Kanda of Mylan, Willem Pretorius of Alere, and Iain Barton of Imperial Health Sciences discussed the specific pharmaceutical, diagnostics, and logistics innovations needed to achieve 90-90-90.

PFSCM Supply Lines Blog

PFSCM Supply Lines is a platform to share our health supply chain knowledge and the latest public health news with our stakeholders and interested parties.

Smiling Woman
Warehouse Worker
Smiling Child